Mitotane (2,4′-DDD), Antineoplastic Agent

Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions. - Mechanism of Action & Protocol.

Fluphenazine-d₈ MedChemExpress (MCE) Life Science Reagents

Mitotane cancer drug molecule. Skeletal formula Stock Vector Image & Art - Alamy

antineoplastic MedChemExpress (MCE) Life Science Reagents

Mitotan 53-19-0 wiki

Chemical Name : Mitotane-d4

Mitotane - an overview

Frontiers Neurological adverse events of mitotane in adrenocortical carcinoma: results of a pilot study

Schematic representation of mitotane metabolism [59, 60, 65-67].

Mitotane - LiverTox - NCBI Bookshelf

Mitotane 500mg Tablets (Lysodren), Bristol-Myers at Rs 68000/bottle in Raipur