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What are TILs and why are they important ? - International TILS Working Group

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INTRODUCTION AND RATIONALE 1. Anti-tumor immune response a) Evading immune response, an emerging hallmark of cancer Human tumor pathogenesis has been traditionally seen as a multistep process through which normal cells progressively acquire the capacity to transform, the so-called “hallmarks of cancer” (Hanahan et al., 2000) (Figure 1). Thus, tumor pathogenesis is generally considered to

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