Single-cell analysis of Crohn's disease reveals a detailed picture of inflammation in the gut

Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn
Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes inflammation throughout the gut, leading to symptoms including abdominal pain, diarrhea, and weight loss. The disease is difficult to treat and often requires hospitalization.

Frontiers Identification of a Disease-Associated Network of Intestinal Immune Cells in Treatment-Naive Inflammatory Bowel Disease

Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn's disease - Mucosal Immunology

David Parry-Smith posted on LinkedIn

A study explores cell-cell interactions in inflammatory bowel disease

Gastrointestinal Inflammation and the Gut Microbiome - EMJ

Reconstructing how zebrafish embryos develop, cell by cell

Immune responses in chronic inflammatory bowel diseases - New population of immune cells that is highly abundant in Crohn's disease patients

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Science in Boston

single cell analysis of fecal washes reveals diverse cell type

Jessica Cabral Laverty on LinkedIn: Single-cell analysis of

Single-cell RNA sequencing reveals dysregulated cellular programmes in the inflamed epithelium of Crohn's disease patients

Stricturing Crohn's Disease Single-Cell RNA Sequencing Reveals Fibroblast Heterogeneity and Intercellular Interactions - ScienceDirect